Opioids present with a syndrome which includes miosis, coma, respiratory depression and vomiting. A rapid response to naloxone is usual if hypoxic brain damage or other events have not been superimposed. The treatment is primarily supportive, although naloxone may also be used in certain circumstances. In recreational overdoses (i.e. dependent patients), a withdrawal reaction to non-titrated doses naloxone is common.
This topic describes: Mechanism, Clinical (Toxic) Symptoms and Opiate Abuse Treatment abuse.